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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Nycomed Pharma
Curated by
ChEMBL
Ligand
BDBM50320989
(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1
(Homo sapiens (Human))
Nycomed Pharma
Curated by
ChEMBL
Ligand
BDBM50320989
(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
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Affinity Data
IC50: 1.26E+4nM
Assay Description:
Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin receptor
(Homo sapiens (Human))
Nycomed Pharma
Curated by
ChEMBL
Ligand
BDBM50320989
(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
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Copy InChI
Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI