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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed