Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

LigandBDBM50383737(CHEMBL2030401)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminus Myc-tagged human CDC7 expressed in Escherichia coli by chemiluminescence assay in presence of ATPMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

LigandBDBM50383737(CHEMBL2030401)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminus His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

LigandBDBM50383737(CHEMBL2030401)Copy SMILESCopy InChI

Affinity DataIC50:  566nMAssay Description:Inhibition of CDC7 in human MDA-MB-231T cells assessed as inhibition of MCM2 phosphorylation at Ser53 after 4 hrsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI