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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human))
Amgen
US Patent
Ligand
BDBM124350
(CHEMBL2071607 | US8759532, 1)
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Affinity Data
IC50: 112nM
T: 2°C
Assay Description:
To check the inhibition profile, 5 μL of serial diluted compounds were incubated with 5 μL of diluted PDE10 enzyme (BPS Bioscience, San Die...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
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US Patent
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Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM124350
(CHEMBL2071607 | US8759532, 1)
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Affinity Data
IC50: 5.77E+3nM
Assay Description:
Inhibition of CK1delta by Lance assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
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Target
Casein kinase I isoform gamma-2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM124350
(CHEMBL2071607 | US8759532, 1)
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Affinity Data
IC50: 6.56E+3nM
Assay Description:
Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblotting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Casein kinase I isoform alpha
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM124350
(CHEMBL2071607 | US8759532, 1)
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Affinity Data
IC50: 1.21E+4nM
Assay Description:
Inhibition of CK1alpha by Lance assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM124350
(CHEMBL2071607 | US8759532, 1)
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Affinity Data
IC50: 3.08E+4nM
Assay Description:
Inhibition of GSK3beta by AlphaScreen assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI