Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cell division cycle 7-related protein kinase
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM50337330
(5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 56.3nM
pH: 7.5
Assay Description:
11 data point. Cdc7 kinase assays were carried out in 25 mM HEPES, pH 7.5, 1 mM DTT, 10 mM MgCl2, 100 μM Na3VO4, and 0.075 mg/ml Triton X-100 u...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50337330
(5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 70nM
Assay Description:
Inhibition of GSK3-beta after 1 hr
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50337330
(5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 285nM
Assay Description:
Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50337330
(5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.65E+5nM
Assay Description:
Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI