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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM89825
(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
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Affinity Data
IC50: 280nM
Assay Description:
Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assay
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM89825
(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
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Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...
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Target Info
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antibodypedia
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Article
PubMed
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM89825
(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
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Affinity Data
IC50: 9.90E+3nM
Assay Description:
Inhibition of human recombinant ARTD1 by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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Target
Protein skinhead-1
(Caenorhabditis elegans)
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM89825
(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
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Affinity Data
IC50: 1.92E+4nM
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Target Info
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MMDB
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KEGG
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B.MOAD
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Target
Heat shock protein hsp-16.2
(Caenorhabditis elegans)
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM89825
(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
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Affinity Data
IC50: >6.40E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
Corticotropin-releasing factor-binding protein
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM89825
(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
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Affinity Data
EC50: >5.30E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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PC cid
PC sid
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In Depth
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PCBioAssay
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