Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50311424(7-((3',4'-difluorobiphenyl-4-ylsulfonyl)methyl)-2,...)Copy SMILESCopy InChI

Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMotilin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50311424(7-((3',4'-difluorobiphenyl-4-ylsulfonyl)methyl)-2,...)Copy SMILESCopy InChI

Affinity DataEC50:  25.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50311424(7-((3',4'-difluorobiphenyl-4-ylsulfonyl)methyl)-2,...)Copy SMILESCopy InChI

Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human gherlin receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI