Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Prostaglandin E synthase
(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by
ChEMBL
Ligand
BDBM50434668
(CHEMBL2387503)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.10nM
Assay Description:
Inhibition of mPGES1 (unknown origin)-mediated PGE2 synthesis transfected in HEK293 cells coexpressing COX1 using arachidonic acid as substrate prein...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin E synthase
(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by
ChEMBL
Ligand
BDBM50434668
(CHEMBL2387503)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Inhibition of mPGES1-mediated PGE2 release in IL1alpha-stimulated human A549 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by
ChEMBL
Ligand
BDBM50434668
(CHEMBL2387503)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+3nM
Assay Description:
Inhibition of thromboxane synthase (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Leukotriene C4 synthase
(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by
ChEMBL
Ligand
BDBM50434668
(CHEMBL2387503)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+3nM
Assay Description:
Inhibition of LTC4S (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by
ChEMBL
Ligand
BDBM50434668
(CHEMBL2387503)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes after 10 mins by LC/MS/MS analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by
ChEMBL
Ligand
BDBM50434668
(CHEMBL2387503)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes after 10 mins by LC/MS/MS analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by
ChEMBL
Ligand
BDBM50434668
(CHEMBL2387503)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes after 10 mins by LC/MS/MS analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI