Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University

US Patent

LigandBDBM246089(US9433622, DMX- 165)Copy SMILESCopy InChI

Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University

US Patent

LigandBDBM246089(US9433622, DMX- 165)Copy SMILESCopy InChI

Affinity DataIC50: <30nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI