Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Carbonic anhydrase 7
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Inhibition of recombinant human CA7 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 45nM
Assay Description:
Inhibition of recombinant human CA12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 2
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 58nM
Assay Description:
Inhibition of recombinant human CA2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 6
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 98nM
Assay Description:
Inhibition of recombinant human CA6 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 126nM
Assay Description:
Inhibition of recombinant human CA9 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 172nM
Assay Description:
Inhibition of recombinant human CA13 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 14
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 677nM
Assay Description:
Inhibition of recombinant human CA14 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 922nM
Assay Description:
Inhibition of recombinant human CA1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 939nM
Assay Description:
Inhibition of recombinant human CA4 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5A, mitochondrial
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.43E+3nM
Assay Description:
Inhibition of recombinant human CA5a preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5B, mitochondrial
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.33E+3nM
Assay Description:
Inhibition of recombinant human CA5b preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydra...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 3
(Human)
University of Florence
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of recombinant human CA3 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
POU domain, class 5, transcription factor 1
(Human)
Shin Nippon Biomedical Laboratories
US Patent
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.76E+4nM
Assay Description:
An existing amount of the OCT3 protein can be estimated from an amount of a compound free in the extracellular fluid in a method similar to a method ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
US Patent
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 2
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.35E+5nM
Assay Description:
Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Human)
Amgen
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Rat)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50103514
(CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI