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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
P2X purinoceptor 4
(Homo sapiens (Human))
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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Article
PubMed
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Target
Bcl-2-related protein A1
(Mus musculus (Mouse))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
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Affinity Data
IC50: >1.00E+5nM
pH: 7.0 T: 2°C
Assay Description:
The aim is to identify chemical probes of Bfl-1 through a fluorescence polarization assay (FPA) using FITC-Bid BH3 peptide. 1) Dose-response curves c...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
KEGG
PC cid
PC sid
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In Depth
Details
PCBioAssay
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Target
Bcl-2-related protein A1
(Mus musculus (Mouse))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
In Depth
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PCBioAssay
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Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus)
Bial
Curated by
ChEMBL
Ligand
BDBM34179
(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
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Affinity Data
IC50: <1.61E+5nM
Assay Description:
Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI