Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL

LigandBDBM50574274(CHEMBL4860970)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL

LigandBDBM50574274(CHEMBL4860970)Copy SMILESCopy InChI

Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI