Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50303037((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDickkopf-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50303037((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-...)Copy SMILESCopy InChI

Affinity DataEC50:  630nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-catenin signaling in osteosasrcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI