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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Ornithine decarboxylase
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
Ki: 3.90E+4nM
Assay Description:
The apparent dissociation constant for irreversible inhibition of rat liver ornithine decarboxylase (ODC)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
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Article
PubMed
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Target
60 kDa heat shock protein, mitochondrial
(Homo sapiens)
Indiana University
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human mitochondrial HSP60/HSP10 expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding pre...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
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ChEBI
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Article
PubMed
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Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Escherichia coli GroEL/GroES expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preinc...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
KEGG
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PC sid
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In Depth
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Article
PubMed
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Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
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ChEBI
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Article
PubMed
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Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
KEGG
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In Depth
Details
Article
PubMed
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
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Target Info
PDB
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antibodypedia
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Ligand Info
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ChEBI
CHEMBL
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In Depth
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Article
PubMed
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Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+5nM
Assay Description:
Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
60 kDa heat shock protein, mitochondrial
(Homo sapiens)
Indiana University
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+5nM
Assay Description:
Inhibition of human mitochondrial HSP60/HSP10-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured M...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
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PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitochondrial 2-oxodicarboxylate carrier
(Homo sapiens)
Michigan State University
Curated by
ChEMBL
Ligand
BDBM50028197
(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
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Affinity Data
IC50: 2.52E+5nM
Assay Description:
Inhibition of ODC (unknown origin) expressed in Escherichia coli after 30 mins in presence of [1-14C] L-ornithine by liquid scintillation counter ana...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Ornithine decarboxylase
(Homo sapiens (Human))
TBA
Ligand
BDBM50487426
(L-Eflornithine)
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Affinity Data
Kd: 3.90E+4nM
Assay Description:
Binding affinity to ODC (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
KEGG
PC cid
PC sid
In Depth
Details
Article
Copy BDB DOI