Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266840(CHEMBL4089707 | US11072585, Example 56)
Affinity DataIC50:  67nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266840(CHEMBL4089707 | US11072585, Example 56)
Affinity DataIC50:  270nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266840(CHEMBL4089707 | US11072585, Example 56)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266840(CHEMBL4089707 | US11072585, Example 56)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant human LOXL2 expressed in human whole blood assessed as reduction of H2O2 production from oxidative deamination of DAP prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266840(CHEMBL4089707 | US11072585, Example 56)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed