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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50:  75.1nMAssay Description:Table 9: Human LOX amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media (BSA-contain...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50:  209nMAssay Description:Table 9: The amine oxidase activity was evaluated by measuring Amplex Red fluorescence using commercially available purified, recombinant human LOXL2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media (non BSA-containing) from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media (non BSA-containing) from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: <300nMAssay Description:Table 8: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media (non BSA-contain...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media (non BSA-containing) from...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50: <300nMAssay Description:Table 8: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media (non BSA-contain...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysyl oxidase homolog 3(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50:  1.21E+3nMAssay Description:Table 9: The amine oxidase activity was evaluated by measuring Amplex Red fluorescence using commercially available purified, recombinant human LOXL3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase (LOX)(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM461421(US10774069, Compound 1 | US11072585, Example 120 |...)
Affinity DataIC50:  4.70E+4nMAssay Description:Table 9: Human LOX amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media (BSA-contain...More data for this Ligand-Target Pair
In DepthDetails US Patent