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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
Pharmakea
US Patent
Ligand
BDBM50232693
(CHEMBL4072524 | US11358936, Compound 2-3)
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Affinity Data
IC50: <300nM
Assay Description:
LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...
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Target Info
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UniProtKB/SwissProt
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US Patent
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Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
Pharmakea
US Patent
Ligand
BDBM50232693
(CHEMBL4072524 | US11358936, Compound 2-3)
Copy SMILES
Copy InChI
Affinity Data
IC50: 321nM
Assay Description:
Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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