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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50526749
(CHEMBL4456211 | US10807974, Example 94 | US1099508...)
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Affinity Data
IC50: 606nM
Assay Description:
Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50526749
(CHEMBL4456211 | US10807974, Example 94 | US1099508...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50526749
(CHEMBL4456211 | US10807974, Example 94 | US1099508...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50526749
(CHEMBL4456211 | US10807974, Example 94 | US1099508...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50526749
(CHEMBL4456211 | US10807974, Example 94 | US1099508...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+3nM
Assay Description:
LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.Assay Plates:Black, flat bottom 96 well platesProcedure:1. Dilute LOX en...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50526749
(CHEMBL4456211 | US10807974, Example 94 | US1099508...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+3nM
Assay Description:
LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 min at room temp on a plate shaker.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50526749
(CHEMBL4456211 | US10807974, Example 94 | US1099508...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+3nM
Assay Description:
The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI