Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50:  85nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50:  168nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50:  443nMAssay Description:Inhibition of HDAC3 (unknown origin) using RHKK(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition f...More data for this Ligand-Target Pair
In DepthDetails PubMed