Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataKi: >2.00E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute Of Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Homo sapiens (Human))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human nNOS by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of wild type rat nNOS by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataKd: >4.00E+6nMAssay Description:Displacement of PRP-1 peptide from mouse Tec kinase SH3 domain by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50013712(2-aminopyridin | 2-aminopyridine | CHEMBL21619 | P...)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human HSP90alpha assessed as 2D1H-15N chemical shift perturbation by NMR spectroscopyChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed