Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNT-3 growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50242452(CHEMBL4075690)Copy SMILESCopy InChI

Affinity DataIC50: >8.10E+4nMAssay Description:Inhibition of PK-tagged human TrkC expressed in human U2OS cells assessed as reduction in NT3-induced EA-tagged SHC1 recruitment pretreated for 1 hr ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50242452(CHEMBL4075690)Copy SMILESCopy InChI

Affinity DataIC50: >8.10E+4nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI