Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50238437(CHEMBL4068794)Copy SMILESCopy InChI

Affinity DataIC50:  10nMAssay Description:Binding affinity to TNKS1 in human HeLa cell extract after 2 hrs by HTS assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50238437(CHEMBL4068794)Copy SMILESCopy InChI

Affinity DataIC50:  126nMAssay Description:Inhibition of TNKS1 (unknown origin) expressed in HEK293 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in wnt3a ligand-induced...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI