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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
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Affinity Data
IC50: 7.90nM
Assay Description:
Binding affinity to TNKS1 in human HeLa cell extract after 2 hrs by HTS assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of His-tagged TNKS1 (1091 to 1325 residues) (unknown origin) assessed as reduction in PARsylation of GST-tev-Axin2 preincubated for 30 min...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of TNKS1 (unknown origin) expressed in HEK293 cells co-expressing TCF/LEF luciferase plasmid assessed as reduction in wnt3a ligand-induced...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
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Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP4 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein mono-ADP-ribosyltransferase PARP11
(Homo sapiens)
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
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Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP11 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
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Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP2 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
Copy SMILES
Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP1 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein mono-ADP-ribosyltransferase PARP16
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
Copy SMILES
Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP16 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein mono-ADP-ribosyltransferase PARP14
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
Copy SMILES
Copy InChI
Affinity Data
IC50: <5.01E+3nM
Assay Description:
Binding affinity to PARP14 in human Jurkat cell extract after 45 mins by mass spectrometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50238416
(CHEMBL4087470)
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Affinity Data
IC50: 3.16E+4nM
Assay Description:
Inhibition of human PI3Kgamma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI