Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

LigandBDBM30202(Pyrrolopyridine, 33)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM30202(Pyrrolopyridine, 33)Copy SMILESCopy InChI

Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI