Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50341532(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of Itk after 40 mins by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50341532(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of full length N-terminal His-tagged Aurora A (unknown origin) using fluorescence-labeled FL-Peptide 21 as substrate after 60 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50341532(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50341532(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed