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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50341532
(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
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Affinity Data
Ki: 1.30E+3nM
Assay Description:
Inhibition of Itk after 40 mins by radiometric phosphate incorporation assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Aurora kinase A
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50341532
(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
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Affinity Data
Ki: 3.30E+3nM
Assay Description:
Inhibition of full length N-terminal His-tagged Aurora A (unknown origin) using fluorescence-labeled FL-Peptide 21 as substrate after 60 mins in pres...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Dual specificity protein kinase TTK
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50341532
(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
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Affinity Data
Ki: 5.40E+3nM
Assay Description:
Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B/Inner centromere protein
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50341532
(3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...)
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Affinity Data
Ki: 4.10E+4nM
Assay Description:
Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI