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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50541080(CHEMBL204153)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) expressed in yeast cells using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2/...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))TBA
LigandPNGBDBM50541080(CHEMBL204153)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of S-COMT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase 3(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50541080(CHEMBL204153)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asn274 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50541080(CHEMBL204153)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of recombinant human MMP8 catalytic domain (Phe99 to Gln269 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50541080(CHEMBL204153)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of recombinant human MMP9 catalytic domain (Phe107 to Pro449 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed