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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
German University In Cairo
Curated by
ChEMBL
Ligand
BDBM50469211
(CHEMBL4283503)
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Affinity Data
IC50: 3.20nM
Assay Description:
Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...
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Target Info
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KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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Ligand Info
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Article
PubMed
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
German University In Cairo
Curated by
ChEMBL
Ligand
BDBM50469211
(CHEMBL4283503)
Copy SMILES
Copy InChI
Affinity Data
IC50: 43nM
Assay Description:
Inhibition of DYRK1A in human HeLa cells harboring GFP-SF3b1-NT assessed as reduction in SF3b1 phosphorylation at T343 residue after 18 hrs by Wester...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
German University In Cairo
Curated by
ChEMBL
Ligand
BDBM50469211
(CHEMBL4283503)
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Affinity Data
IC50: 73nM
Assay Description:
Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...
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Article
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Target
Serine/threonine-protein kinase haspin
(Homo sapiens (Human))
German University In Cairo
Curated by
ChEMBL
Ligand
BDBM50469211
(CHEMBL4283503)
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Affinity Data
IC50: 76nM
Assay Description:
Inhibition of human GST-tagged haspin expressed in baculovirus expression system in presence of 100 uM ATP
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Target Info
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Article
PubMed
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Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
German University In Cairo
Curated by
ChEMBL
Ligand
BDBM50469211
(CHEMBL4283503)
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Affinity Data
IC50: 270nM
Assay Description:
Inhibition of recombinant human GST-tagged CLK1 (129 to 484 residues) expressed in Escherichia coli using GRSRSRSRSRSRSRSR as substrate after 15 mins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI