Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50160847(1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed