Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 18 hits in this display   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi:  20nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi:  220nMAssay Description:Inhibition of ERKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi:  480nMAssay Description:Inhibition of PKCdMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of GSKp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of EPHB3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKCaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of PKAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataIC50:  1.85E+3nMAssay Description:Antiproliferative activity against human SJSA1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataIC50:  2.34E+3nMAssay Description:Antiproliferative activity against human RKO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataIC50:  2.41E+3nMAssay Description:Antiproliferative activity against human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataIC50:  2.49E+3nMAssay Description:Antiproliferative activity against human H460a cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataIC50:  3.34E+3nMAssay Description:Antiproliferative activity against human MDA435 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Technical University of Dortmund

LigandPNGBDBM153752(ROCHE screening, 70)
Affinity DataIC50:  6.09E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50205477((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...)
Affinity DataIC50:  6.58E+3nMAssay Description:Antiproliferative activity against human SW480 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed