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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-{3-(4-phenylpiperazin-1-ylmethyl)benzyl}resorufin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataIC50: >1.58E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human gherlin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311413(CHEMBL1078595 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed