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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  71nMAssay Description:Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  71nMAssay Description:Inhibition of human TNKS2 (956 to 1161 and 873 to 1161) using 500 nM NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  370nMAssay Description:Inhibition of human TNKS1 (1030 to 1317) using NAD substrate after 20 mins incubation by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of full-length human ARTD2 using 500 nM NAD substrate after 3 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human ARTD10 (809 to 1017) using 500 nM NAD substrate after 2.5 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of full-length human ARTD1 using 500 nM NAD substrate after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ARTD7 (460 to 656) using 250 nM NAD substrate after 2 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of full-length human ARTD3 using 500 nM NAD substrate after 1 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50104286(CHEMBL3593715)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed