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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
22
hits in this display
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
Ki: 16nM
Assay Description:
Binding affinity to KDM5B (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
Ki: 26nM
Assay Description:
Binding affinity to KDM4A (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 66nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 121nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 134nM
Assay Description:
Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 5C
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 202nM
Assay Description:
Inhibition of KDM5C (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 248nM
Assay Description:
Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 265nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 477nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 559nM
Assay Description:
Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 564nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.11E+3nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.44E+3nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.21E+3nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 3A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.13E+3nM
Assay Description:
Inhibition of KDM3A (unknown origin) by Alphascreen assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.68E+3nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.11E+4nM
Assay Description:
Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 2A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.25E+4nM
Assay Description:
Inhibition of KDM2A (unknown origin) by Alphascreen assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.60E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal KDM5B (26 to 772 residues) fused with ePL-tagged C-terminal transfected in HEK293T cells measured af...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
EC50: 9.10E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513346
(CHEMBL4525269)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.64E+4nM
Assay Description:
Inhibition of full length human wild type KDM5B transfected in HeLa cells assessed as decrease in demethylation of H3K4Me3 measured after 24 hrs by c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI