Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50496340(CHEMBL3124953)Copy SMILESCopy InChI

Affinity DataIC50:  529nMAssay Description:Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50496340(CHEMBL3124953)Copy SMILESCopy InChI

Affinity DataKd:  952nMAssay Description:Binding affinity to human menin by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI