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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of KDM4AMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of KDM4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of KDM2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  1.89E+5nMAssay Description:Inhibition of FIH (unknown origin) assessed as hydroxylation of HIF1alphaCAD by MALDI-TOF-MS analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibition of FTO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  4.24E+5nMAssay Description:Inhibition of N-terminal His-tagged human full length ALKBH2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition of N-terminal His-tagged human FIH expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))TBA
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  3.60E+6nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))TBA
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  7.30E+6nMAssay Description:Inhibition of N-terminal His-tagged human PHD2 catalytic domain (181 to 426 residues) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  8.30E+6nMAssay Description:Inhibition of human ALKBH3 using ss-m1A DNA as substrate by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed