Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131952(2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131952(2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131952(2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131952(2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131952(2-(Biphenyl-4-ylmethylsulfanyl)-5-(1,3-dioxo-1,3-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed