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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
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Affinity Data
IC50: 11nM
Assay Description:
Inhibitory activity against human thromboxane synthetase
More data for this Ligand-Target Pair
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Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Thromboxane A2 synthase inhibitory activity was measured from inhibition of thromboxane B2 production in human platelet microsomes
More data for this Ligand-Target Pair
Target Info
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Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
In vitro inhibition of thromboxane synthase (TXA2) in human platelet microsomes [reduced formation of TXB2 from prostaglandin H2(PGH2)]
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
MCE
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Article
PubMed
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Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
In vitro inhibition of TXB2 production by incubating prostaglandin H2 with human platelet microsomes.
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Target
Thromboxane-A synthase
(Rattus norvegicus)
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
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Affinity Data
IC50: 200nM
Assay Description:
Tested in vitro against TXA2 synthetase inhibitory activity in rat platelet
More data for this Ligand-Target Pair
Target Info
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PubMed
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Target
Thromboxane-A synthase
(Rattus norvegicus)
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
Tested in vitro against TXA2 synthetase inhibitory activity in rat whole blood
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Tested in vitro against TXA2 synthetase inhibitory activity in human platelet
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Tested in vitro against TXA2 synthetase inhibitory activity in human platelet
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Rattus norvegicus)
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 640nM
Assay Description:
In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 900nM
Assay Description:
Tested in vitro against TXA2 synthetase inhibitory activity in human whole blood
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40E+3nM
Assay Description:
Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
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CHEMBL
MCE
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Southern Research Institute
Curated by
PubChem BioAssay
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
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Affinity Data
IC50: 3.43E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
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In Depth
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PCBioAssay
Copy BDB DOI
Target
Thromboxane-A synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibitory activity against Thromboxane A2 synthase in human platelet microsome
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
Patents
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In Depth
Details
Article
Copy BDB DOI
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Pharmacia-Farmitalia Carlo Erba
Curated by
ChEMBL
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Southern Research Institute
Curated by
PubChem BioAssay
Ligand
BDBM50017896
((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >5.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
KEGG
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PC sid
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In Depth
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PCBioAssay
Copy BDB DOI