Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL

LigandBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)Copy SMILESCopy InChI

Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL

LigandBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)Copy SMILESCopy InChI

Affinity DataIC50:  580nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL

LigandBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI