Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
Caspase-3(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)Caspase-7(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Ki: 130nM ΔG°: -39.3kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-8(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Ki: 330nM ΔG°: -37.0kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-1(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Ki: 3.20E+3nM ΔG°: -31.4kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-6(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Ki: 9.70E+3nM ΔG°: -28.6kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-5(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Ki: 6.30E+4nM ΔG°: -24.0kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-2(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Ki: 6.40E+4nM ΔG°: -23.9kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
Caspase-4(Homo sapiens (Human))Sunesis Pharmaceuticals
BDBM226((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Ki: 1.00E+5nM ΔG°: -22.8kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair