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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Caspase-1
(Homo sapiens (Human))
Pfizer
Ligand
BDBM12043
((3S)-3-{[(benzyloxy)carbonyl]amino}-4-oxo-9-phenyl...)
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Affinity Data
Ki: 1.19E+5nM ΔG°: -23.3kJ/mole
pH: 7.0 T: 2°C
Assay Description:
The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Caspase-1
(Homo sapiens (Human))
Pfizer
Ligand
BDBM50139696
(3-Benzyloxycarbonylamino-4-oxo-9-phenyl-nonanoic a...)
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Affinity Data
Ki: 1.19E+5nM
Assay Description:
Inhibitory activity against caspase-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-1
(Homo sapiens (Human))
Pfizer
Ligand
BDBM50139696
(3-Benzyloxycarbonylamino-4-oxo-9-phenyl-nonanoic a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.03E+6nM
Assay Description:
Inhibitory activity against caspase-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI