Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12043((3S)-3-{[(benzyloxy)carbonyl]amino}-4-oxo-9-phenyl...)
Affinity DataKi:  1.19E+5nM ΔG°:  -23.3kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM50139696(3-Benzyloxycarbonylamino-4-oxo-9-phenyl-nonanoic a...)
Affinity DataKi:  1.19E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM50139696(3-Benzyloxycarbonylamino-4-oxo-9-phenyl-nonanoic a...)
Affinity DataIC50:  1.03E+6nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed