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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Platelet-activating factor acetylhydrolase [136-227]
(Sus scrofa)
Fisons
Curated by
ChEMBL
Ligand
BDBM50040461
((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...)
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Affinity Data
IC50: 15nM
Assay Description:
In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
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Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
Fisons
Curated by
ChEMBL
Ligand
BDBM50040461
((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...)
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Affinity Data
IC50: 21nM
Assay Description:
Compound was tested for in vitro activity against s-phospholipase A2 (s-PLA2) isolated from human platelets
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Platelet-activating factor acetylhydrolase [136-227]
(Sus scrofa)
Fisons
Curated by
ChEMBL
Ligand
BDBM50040461
((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Compound was tested for in vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and micellar substrate with deoxycholate (DOC)
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI