Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50507425(CHEMBL4458708)Copy SMILESCopy InChI

Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetEgl nine homolog 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50507425(CHEMBL4458708)Copy SMILESCopy InChI

Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50507425(CHEMBL4458708)Copy SMILESCopy InChI

Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI