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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Alpha-ketoglutarate-dependent dioxygenase FTO
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: 80nM
Assay Description:
Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 (DE3) incubated for 10 mins using ...
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MMDB
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Target
Alpha-ketoglutarate-dependent dioxygenase FTO
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incub...
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PDB
MMDB
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KEGG
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antibodypedia
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Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: 2.20E+3nM
Assay Description:
Inhibition of recombinant N-terminal hexahistidine-tagged human PDH2 (181 to 426 residues) expressed in Escherichia coli BL21 (DE3) preincubated for ...
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Target
Lysine-specific demethylase 6B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: 1.96E+4nM
Assay Description:
Inhibition of human KDM6B preincubated for 15 mins followed by substrate addition and measured after 5 mins using H3(21-44)K27Me3-GK-biotin peptide a...
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Target
Hypoxia-inducible factor 1-alpha inhibitor
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: 4.59E+4nM
Assay Description:
Inhibition of human FIH preincubated for 15 mins followed by substrate addition and measured after 15 mins using ankyrin peptide HLEVVKLLLEAGADVNAQDK...
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Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: 4.63E+4nM
Assay Description:
Inhibition of human KDM5B preincubated for 15 mins followed by substrate addition and measured after 20 mins using H3(1-21)K4Me3-GGK-Biotin peptide a...
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Target
Lysine-specific demethylase 3A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human KDM3A preincubated for 15 mins followed by substrate addition and measured after 5 mins using H3(1-21)K9Me2-GGK-Biotin peptide as...
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Target
Lysine-specific demethylase 4C
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human KDM4C preincubated for 15 mins followed by substrate addition and measured after 15 mins using H3(1-21)K9Me3-GGK-Biotin peptide a...
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Target
Lysine-specific demethylase 2A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human KDM2A preincubated for 15 mins followed by substrate addition and measured after 30 mins using Biotin-H3(28-48)K36Me2 peptide as ...
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Target
Alpha-ketoglutarate-dependent dioxygenase FTO
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50606681
(CHEMBL5219846)
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Affinity Data
Kd: 340nM
Assay Description:
Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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B.MOAD
antibodypedia
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3D Structure (crystal)
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