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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Egl nine homolog 1
(Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
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Affinity Data
IC50: 13.7nM
Assay Description:
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Egl nine homolog 1
(Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
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Affinity Data
IC50: 64nM
Assay Description:
Inhibition of FITC-HIF1alpha (556 to 574 residues) binding to PHD2 (181 to 426 residues) (unknown origin) by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
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Copy InChI
Affinity Data
IC50: 1.37E+4nM
Assay Description:
Inhibition of HIF-PHD2 (unknown origin) expressed in insect Hi5 cells using peptide as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP1A2 (unknown origin) using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH measured after 20 mins by L...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2C9 (unknown origin) using diclofenac as substrate preincubated for 5 mins followed by addition of NADPH measured after 20 mins by L...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin) using dextromethorphan as substrate preincubated for 5 mins followed by addition of NADPH measured after 20 min...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin) using midazolam as substrate preincubated for 5 mins followed by addition of NADPH measured after 20 mins by LC...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50318679
(CHEMBL4162752 | US10889546, Example 44)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin) using testosterone as substrate preincubated for 5 mins followed by addition of NADPH measured after 20 mins by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI