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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataIC50:  150nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition human recombinant aldose reductase 1 by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSorbitol dehydrogenase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataIC50:  1.63E+5nMAssay Description:Inhibition sorbitol dehydrogenase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
The Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataKd:  150nMAssay Description:Dissociation constant for binding to SH2 domain of Fyn protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
The Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataKd:  35nMAssay Description:Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
The Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataKd:  1.13E+4nMAssay Description:Dissociation constant for binding to SH2 domain of Growth factor receptor bound protein 2, Grb2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed