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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Aldo-keto reductase family 1 member B1
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50022182
((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
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Affinity Data
IC50: 150nM
Assay Description:
Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)
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Target Info
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Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM50022182
((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
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Affinity Data
IC50: 2.08E+4nM
Assay Description:
Inhibition human recombinant aldose reductase 1 by spectrophotometric analysis
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Target
Sorbitol dehydrogenase
(Homo sapiens (Human))
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM50022182
((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
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Affinity Data
IC50: 1.63E+5nM
Assay Description:
Inhibition sorbitol dehydrogenase by spectrophotometric analysis
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Target Info
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Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
The Albert Einstein College Of Medicine Of Yeshiva University
Curated by
ChEMBL
Ligand
BDBM50022182
((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
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Affinity Data
Kd: 150nM
Assay Description:
Dissociation constant for binding to SH2 domain of Fyn protein kinase
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
The Albert Einstein College Of Medicine Of Yeshiva University
Curated by
ChEMBL
Ligand
BDBM50022182
((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
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Affinity Data
Kd: 35nM
Assay Description:
Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase
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Target
Growth factor receptor-bound protein 2
(Homo sapiens (Human))
The Albert Einstein College Of Medicine Of Yeshiva University
Curated by
ChEMBL
Ligand
BDBM50022182
((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
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Affinity Data
Kd: 1.13E+4nM
Assay Description:
Dissociation constant for binding to SH2 domain of Growth factor receptor bound protein 2, Grb2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
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In Depth
Details
Article
PubMed
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