Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 18 hits in this display   

TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498675(CHEMBL3621881)Copy SMILESCopy InChI

Affinity DataIC50:  63nMAssay Description:Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498680(CHEMBL3621878)Copy SMILESCopy InChI

Affinity DataIC50:  126nMAssay Description:Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498675(CHEMBL3621881)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498663(CHEMBL3621882)Copy SMILESCopy InChI

Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498680(CHEMBL3621878)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498675(CHEMBL3621881)Copy SMILESCopy InChI

Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of KDM4C (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate incubated for 15 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498675(CHEMBL3621881)Copy SMILESCopy InChI

Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of KDM4A (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498680(CHEMBL3621878)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of KDM4C (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate incubated for 15 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498680(CHEMBL3621878)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of KDM6B (unknown origin) using H3(21-44)K27Me3-GK-biotin substrate incubated for 5 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498663(CHEMBL3621882)Copy SMILESCopy InChI

Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of KDM6B (unknown origin) using H3(21-44)K27Me3-GK-biotin substrate incubated for 5 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 3A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498680(CHEMBL3621878)Copy SMILESCopy InChI

Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of KDM3A (unknown origin) using H3(1-21)K9Me2-GGK-biotin substrate incubated for 5 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498680(CHEMBL3621878)Copy SMILESCopy InChI

Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of KDM4A (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498663(CHEMBL3621882)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM4E (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 3A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498675(CHEMBL3621881)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM3A (unknown origin) using H3(1-21)K9Me2-GGK-biotin substrate incubated for 5 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498663(CHEMBL3621882)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM4C (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate incubated for 15 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498680(CHEMBL3621878)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM4E (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498675(CHEMBL3621881)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM6B (unknown origin) using H3(21-44)K27Me3-GK-biotin substrate incubated for 5 mins by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL

LigandBDBM50498675(CHEMBL3621881)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of KDM4E (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI