Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 27 hits in this display
BDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
IC50: 12nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: <100nMAssay Description:Jarid1B: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction condit...More data for this Ligand-Target Pair
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
IC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: <100nMAssay Description:Jarid1A: The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability ...More data for this Ligand-Target Pair
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
BDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
BDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
IC50: 550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
BDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
IC50: 550nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
IC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: 550nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
BDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
IC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
BDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
IC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: 550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
BDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
IC50: 550nMAssay Description:Jarid1A: The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability ...More data for this Ligand-Target Pair
BDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
IC50: 550nMAssay Description:Jarid1B: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction condit...More data for this Ligand-Target Pair
BDBM314143(3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]a...)
IC50: >2.00E+3nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair