Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetEgl nine homolog 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL

LigandBDBM50446891(CHEMBL3115314 | US10246442, Example 61 | US1097506...)Copy SMILESCopy InChI

Affinity DataIC50:  50nMAssay Description:Inhibition of PHD2 (181 to 417) (unknown origin) using HIF-1alpha peptide as substrate assessed as 2-Oxoglutarate conversion to succinic acid preincu...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
TBA

US Patent

LigandBDBM50446891(CHEMBL3115314 | US10246442, Example 61 | US1097506...)Copy SMILESCopy InChI

Affinity DataIC50:  50.1nMAssay Description:The PHD enzymatic assay was performed in 0.5 ml of reaction mixture containing the following: purified PHD2181-417 polypeptide (3 μg), synthetic...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetEgl nine homolog 1 [182-426](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent

LigandBDBM50446891(CHEMBL3115314 | US10246442, Example 61 | US1097506...)Copy SMILESCopy InChI

Affinity DataIC50:  50.1nMAssay Description:The PHD enzymatic assay was performed in 0.5 ml of reaction mixture containing the following: purified PHD2181-417 polypeptide (3 μg), synthetic...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI