Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universite De Lyon

LigandPNGBDBM34110(glucopyranosylidene-spiro-isoxazoline, 4e)
Affinity DataKi:  630nM ΔG°:  -36.0kJ/molepH: 6.8 T: 2°CAssay Description:Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universite De Lyon

LigandPNGBDBM34110(glucopyranosylidene-spiro-isoxazoline, 4e)
Affinity DataIC50:  630nMAssay Description:Binding affinity to rabbit muscular GPb by NMR binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM34110(glucopyranosylidene-spiro-isoxazoline, 4e)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of glycogen phosphorylase in human hepatocytes assessed as glucagon stimulated glycogen content after 3 hrs by colorimetric GOD methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM34110(glucopyranosylidene-spiro-isoxazoline, 4e)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of glycogen phosphorylase in human hepatocytes assessed as decrease in glucagon stimulated glucose release after 3 hrs by glucose oxidase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM34110(glucopyranosylidene-spiro-isoxazoline, 4e)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of glycogen phosphorylase in Wistar rat hepatocytes assessed as decrease in glucagon stimulated glucose release after 3 hrs by glucose oxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed