Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50065953((S)-5-chloro-N-(1-(4-hydroxypiperidin-1-yl)-1-oxo-...)Copy SMILESCopy InChI

Affinity DataIC50:  260nMAssay Description:In vitro inhibitory activity against recombinant human liver glycogen phosphorylase a (rHLGPa) catalyzed release of phosphate from glucose-1-phosphat...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Act

Curated by ChEMBL

LigandBDBM50065953((S)-5-chloro-N-(1-(4-hydroxypiperidin-1-yl)-1-oxo-...)Copy SMILESCopy InChI

Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI