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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
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Affinity Data
IC50: 11nM
Assay Description:
Inhibition of TNKS2 (unknown origin)
More data for this Ligand-Target Pair
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of human recombinant TNKS2
More data for this Ligand-Target Pair
Target Info
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of recombinant human N-terminal TEV cleavage site-fused/FLAG-poly his-tagged TNKS2 SAM-PARP domain (613 to 1166 residues) expressed in Esc...
More data for this Ligand-Target Pair
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of recombinant human N-terminal TEV cleavage site-fused/FLAG-poly his-tagged TNKS2 ARC5-SAM-PARP domain (613 to 1166 residues) expressed i...
More data for this Ligand-Target Pair
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Target
Poly [ADP-ribose] polymerase tankyrase-1/tankyrase-2
(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...
More data for this Ligand-Target Pair
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Target
Poly [ADP-ribose] polymerase tankyrase-1/tankyrase-2
(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase re...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
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PubMed
PDB
3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
TBA
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Inhibition of human recombinant TNKS1
More data for this Ligand-Target Pair
Target Info
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
TBA
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Inhibition of recombinant human N-terminal TEV cleavage site-fused/FLAG-poly his-tagged TNKS SAM-PARP domain (1024 to 1327 residues) expressed in Esc...
More data for this Ligand-Target Pair
Target Info
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
TBA
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Inhibition of recombinant human N-terminal TEV cleavage site-fused/FLAG-poly his-tagged TNKS SAM-PARP domain (1024 to 1327 residues) expressed in Esc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
PDB
In Depth
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
TBA
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Inhibition of TNKS1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
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PDB
In Depth
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PubMed
PDB
3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-1/tankyrase-2
(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 78nM
Assay Description:
Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferas...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
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Ligand Info
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-1/tankyrase-2
(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 78nM
Assay Description:
Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferas...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
PDB
In Depth
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.72E+3nM
Assay Description:
Inhibition of human recombinant N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in ...
More data for this Ligand-Target Pair
Target Info
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KEGG
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PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.72E+3nM
Assay Description:
Inhibition of human recombinant N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in ...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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In Depth
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PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.72E+3nM
Assay Description:
Inhibition of PAPR2 (unknown origin)
More data for this Ligand-Target Pair
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Target
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human))
Riken
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
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Affinity Data
IC50: 1.98E+4nM
Assay Description:
Inhibition of human recombinant N-terminal TEV-cleavgae site-fused-FLAG/Polyhis-tagged PARP10 (2 to 583 residues) expressed in Escherichia coli asses...
More data for this Ligand-Target Pair
Target Info
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Target
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human))
Riken
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.98E+4nM
Assay Description:
Inhibition of human recombinant N-terminal TEV-cleavgae site-fused-FLAG/Polyhis-tagged PARP10 (2 to 583 residues) expressed in Escherichia coli asses...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
Riken
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of recombinant human PARP1 expressed in Escherichia coli assessed as reduction in auto-PARylation using histone as substrate measured afte...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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UniProtKB/SwissProt
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Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
Riken
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of PARP1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
PDB
In Depth
Details
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
Riken
Curated by
ChEMBL
Ligand
BDBM50511566
(CHEMBL4448872)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant human PARP1 expressed in Escherichia coli assessed as reduction in auto-PARylation using histone as substrate measured afte...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI