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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
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Affinity Data
IC50: 0.950nM
Assay Description:
Inhibitory concentration against matrix metalloprotease 13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
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Affinity Data
IC50: 0.950nM
Assay Description:
Inhibition of matrix metalloprotease 12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
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Affinity Data
IC50: 5.30nM
Assay Description:
Inhibition of matrix metalloprotease 9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
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Affinity Data
IC50: 8.10nM
Assay Description:
Inhibitory concentration against aggrecanase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of matrix metalloprotease 2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 55nM
Assay Description:
Inhibition of matrix metalloprotease 3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Inhibition of matrix metalloprotease 14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50151732
(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 920nM
Assay Description:
Inhibitory concentration against matrix metalloprotease 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI